Measles is an acute infection caused by Rubeola Virus. After an incubation period of 10-14 days, cough, coryza, fever and a maculopapular rash that begins several days after the initial symptoms characterize the illness. The characteristic oral exanthem, Koplik's spots, is specific for measles and precedes the onset of rash. Serologic testing can aid in the clinical diagnosis. In the absence of a current or recent infection, a demonstration of specific IgG on a serum sample by enzyme immunoassay is evidence of immunity to Rubeola. Acute infection is diagnosed by a demonstration of IgM antibody.
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